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By Bus
From the TGV station in Avignon, take the train to Carpentras, then the bus to Pernes-les-Fontaines (change in Carpentras).
Bus from Avignon to Carpentras
From Marseille Provence Airport, "LER Shuttle Marseille Airport / Carpentras" to Pernes-les-Fontaines, get off at "La Nesque" stop.